The name of Nancy and Andy's "fakery" is Breadsticks and Scones. The cap that bakery employees wear shortens the name of the bakery to "BS" as a joke.
Many of the exterior shots of the show are filmed on location in and around the bedroom community of Stevenson Ranch, California and Santa Clarita, California.
The aerial photo during the intro is of Calabasas, California.
Due to product placement deals, Nancy often carries an "It's a Grind Coffee House" beverage. A Starbucks in Calabasas, California, fills in for "It's a Grind," in the opening credits.
The theme song "Little Boxes", was sung and composed by Malvina Reynolds in 1962.
During the second and third seasons, the opening credits were again accompanied by the Malvina Reynolds song "Little Boxes," but sung instead by a different individual or group each time. Artists who provided covers for openers included Elvis Costello, Death Cab for Cutie, Engelbert Humperdinck (II), Kate McGarrigle and Anna McGarrigle (who sang the song in French), Regina Spektor, Jenny Lewis (I) and Johnathan Rice, Randy Newman (I), Angélique Kidjo, Donovan (I), Billy Bob Thornton, The Shins, Joan Baez, The Decemberists and Linkin Park.
The book Rejuvenile by author Christopher Noxon has appeared several times on the show. Noxon is married to series creator Jenji Kohan. Noxon was also the music supervisor for season one and appeared in the pilot episode as a bear hunter.