The Tonight Show with Conan O'Brien
- On the episode of November 18, 2009, 'Conan OBrien said Heidi Montag and Spencer Pratt are on the show and the audience booed. On the next day's episode, Conan said, "In 17 years in this business, I've never heard an audience respond like this."
- In January 2010, NBC announced that Jay Leno, host of The Tonight Show with Jay Leno, from whom 'Conan OBrien took over the role as host, would have his not-so-well-received The Jay Leno Show move towards the 11:35 PM time-slot and that The Tonight Show with Conan O'Brien would be pushed back to the 12:05 AM time-slot. "The Tonight Show" has never aired that late during its almost 60 years on air. Furthermore, this push-back would have meant that Late Night with Jimmy Fallon, follow-up to O'Brien's own Late Night with Conan O'Brien, would also have been pushed back to a later time-slot, too. When The Jay Leno Show was officially canceled and it became clear that Leno would get his own new show at 11:35 PM, O'Brien released a statement in which he made clear that he didn't like how NBC handled the situation. He also stated that he wouldn't continue hosting The Tonight Show with Conan O'Brien if it was pushed back to a later time-slot. Eventually that month, it was officially announced that Leno would get "The Tonight Show" back on March 1st and that O'Brien will receive a severance payment of about $33 million from NBC.
- During the time of the "Late Night Wars", in January 2010, in which NBC was re-scheduling its Late Night-program, there evolved the "I'm with Coco" movement, which favored 'Conan OBrien over Jay Leno as host (of "The Tonight Show" or anything else) and thought that NBC's behavior towards O'Brien was rude.
- When 'Conan OBrien announced (on January 13, 2010) that he wouldn't continue to host the show if it would be pushed back to another time slot to air, he rather abruptly ended his stint as host of "The Tonight Show". The last episode of The Tonight Show with Conan O'Brien aired on January 22nd, 2010. O'Brien remained under contract with NBC until September 1, 2010.
- At 46 years old, O'Brien is the oldest person to start hosting "The Tonight Show".
- The name of the curtains on the main stage is Golden Sunburst which was created by the design duo of Hutton Wilkinson and Tony Duquette for Jim Thompson Designs.
- This episode aired one day after NBC announced that The Jay Leno Show was being dropped from the prime-time schedule once the 2010 Winter Olympics began on February 12; the network proposed that the show be shortened to a half-hour and moved to the 11:35/10:35c timeslot which Leno had occupied as the previous host of "The Tonight Show" from 1992 to May 2009, with "The Tonight Show" pushed back a half-hour.
- Host 'Conan OBrien discussed the concussion he suffered during the taping of the previous Friday's cancelled show, and showed a tape of the incident in which he slipped on the studio floor during a footrace with Teri Hatcher and hit the back of his head.
