- Reese's horse was Cactus.
- The pilot aired as an episode of The Virginian and was later released theatrically as Backtrack! (1969). Three episodes from the first season of "Laredo" were also edited into a theatrical feature, 1968's Three Guns for Texas (1968).
- Peter Brown used his real life horse, Amigo, on the series.
- Guest stars Claude Akins and George Kennedy were tested for regular roles on the series.
- Title is a riff on the movie The Bitter Tea of General Yen.
- Last show of the series.
