Blythe Danner was hooked on Izzy right from the start. She claimed Izzy is the most multilayered character she has ever played. The producers thought it would take many seasons to get to know everything about Izzy. Alas, Huff was cancelled after just two seasons on the air.
Andy Comeau got the part of Teddy because he didn't play it crazy the way the other actors did in the auditions.
Bob Lowry couldn't imagine anyone but Hank Azaria playing the part of Dr Craig Huffstodt. Indeed its Azaria's favourite role of his own.
The pilot was recorded in Vancouver, but the remainder of the show was filmed in Los Angeles.
Sharon Stone's character mentions people look at her like she has three breasts. There is a character with three breasts in the film Total Recall in which she stars.