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Dr. Derek Shepherd Grey's Anatomy

Dr. Derek Shepherd

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  Played by:
Patrick DempseyPatrick Dempsey
Actor Patrick Dempsey has lived two charming but separate lives on film and TV. From an exuberant, somewhat ...

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Dr. Derek Shepherd Quotes

04x16 - Freedom (1) Season 4 / Episode 16: - Freedom (1)

Dr. Derek Shepherd: [as he is walking up to Meredith, walking around, surrounded by candles] Meredith....
Dr. Meredith Grey: [unaware that Derek is approaching] Stupid, corny, idiotic, I can't believe I did this. Stupid, loser, son of a ... I could be at home instead of ... oh stupid, stupid brain man!
Dr. Derek Shepherd: [smiling] Meredith...
04x04 - The Heart Of The Matter Season 4 / Episode 4: - The Heart Of The Matter

Dr. Derek Shepherd: You know what I talked about with the other Grey? All the things this Grey won't let me say.
Dr. Meredith Grey: You can say anything to me.
Dr. Derek Shepherd: I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old in your arms. I don't want 48 uninterrupted hours. I want a lifetime. [Meredith takes a few steps back]. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay. I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time. Deep down you're still an intern, and you're not ready.
Dr. Meredith Grey: I'm not ready right now, but things can stay the way they are and I'll get ready.
Dr. Derek Shepherd: Things can't stay the way they are. We can still meet in the elevator, the on call room. And maybe you'll get ready, and I'll wait. I'll wait until you're ready.
Dr. Meredith Grey: Okay then.
Dr. Derek Shepherd: Yeah, but what if, what if while I'm waiting I meet someone who is ready to give me what I want from you?
Dr. Meredith Grey: What if you do? [the elevator opens in front of them and Derek steps in]
Dr. Derek Shepherd: I don't know. [the doors close between them]
03x25 - Didn't We Almost Have It All Season 3 / Episode 25: - Didn't We Almost Have It All

Dr. Derek Shepherd: Don't you see? Don't you understand? You're the love of my life. I can't leave you. But you're constantly leaving me. You walk away when you want, you come back when you want. Not everyone. Not your friends. But you leave me. So I'm asking you, if you don't see a future for us, if you're not in this... Please... please just end it because I can't. I'm in it. Put me out of my misery.
03x04 - What I Am Season 3 / Episode 4: - What I Am

Dr. Meredith Grey: You are just one of many men I happen to be dating at the moment.
Dr. Derek Shepherd: Really? How many of us are there?
Dr. Meredith Grey: Uh... well... there's... uh... you... and Finn... and...
Dr. Derek Shepherd: Well forgive me for pointing out the obvious, but I don't see any practitioners of veterinary medicine at your bedside.
Dr. Finn Dandridge: You would if you turned around.
Dr. Derek Shepherd: Ah... Finn.
Dr. Finn Dandridge: Derek.
Dr. Meredith Grey: Can I just say how much it helps that I am on drugs right now.
Dr. Derek Shepherd: So.
Dr. Finn Dandridge: So.
Dr. Derek Shepherd: So, how's life in the animal kingdom?
Dr. Finn Dandridge: 'Bout you, Derek? Slow day? [Derek's pager beeps] If you need to take off that's...
Dr. Derek Shepherd: No, it's fine. I can stay.
Dr. Finn Dandridge: Great.
Dr. Meredith Grey: Great.
Dr. Derek Shepherd: Great.
Dr. George O'Malley: Ok, let's get you prepped and ready-Dr. Shepard. Dr. Finn.
Dr. Meredith Grey: Now all my boys are here. You're all so handsome... and such good kissers.
Dr. George O'Malley: Oh... God...
Dr. Finn Dandridge: Excuse me?
Dr. George O'Malley: She's on drugs.
Dr. Meredith Grey: He's an excellent kisser.
Dr. Finn Dandridge: You two dated?
Dr. Derek Shepherd: You didn't know?
Dr. Meredith Grey: It wasn't a date so much as a... disastrously... uncomfortable... sexual experience.
03x03 - Sometimes A Fantasy Season 3 / Episode 3: - Sometimes A Fantasy

Dr. Finn Dandridge: Hi!
Dr. Derek Shepherd: [shocked] Finn...
Dr. Finn Dandridge: I didn't think you guys would be here! I just wanted to drop this off... it's strawberry ice cream... a patient made it for me...
Dr. Derek Shepherd: A patient's owner...
Dr. Finn Dandridge: It's made from scratch... real strawberries.
Dr. Meredith Grey: I love strawberry ice cream!
Dr. Derek Shepherd: And you remembered...
Dr. Finn Dandridge: I did! I just thought I'd leave it by the door.
Dr. Derek Shepherd: You didn't think it would melt?
Dr. Finn Dandridge: Well you take your chances.
Dr. Derek Shepherd: It worked out for you...
Dr. Finn Dandridge: Mmm...
Dr. Meredith Grey: What exactly is going on here?
Dr. Derek Shepherd: He's crashing our date.
Dr. Finn Dandridge: And where do you think I got that idea?
Dr. Derek Shepherd: I didn't crash your date, it was professional.
Dr. Finn Dandridge: You can't operate without her?
Dr. Derek Shepherd: I certainly operate well with her!
Dr. Meredith Grey: Enough! This is not dating... I want moonlight and flowers and candy... and people trying to feel me up... nobody is trying to feel me up! Nobody is even looking at me! I'm an intern... do the two of you have any idea how much effort it takes to do all this? I'm waxed, I plucked and have a clean top on and the two of you are looking at each other!
Dr. Derek Shepherd: Meredith we...
Dr. Meredith Grey: NO! My fantasy is not two men looking at each other!
Dr. Finn Dandridge: We didn't...
Dr. Meredith Grey: No talking until one of you figures out how to put on a date! I want heat, I want romance... dammit! I want to feel like a frickin' lady! [walks into her house]
03x01 - Time Has Come Today Season 3 / Episode 1: - Time Has Come Today

Dr. Derek Shepherd: It means you have a choice. You have a choice to make. And I don't want to rush you into making the decision before you're ready. This morning I was going to come over... I was going to say... What I wanted to say was... But now all I can say is that... I'm in love with you. I've been in love with you for, ever. I'm a little late, I know I'm a little late in telling you that. I, I just, I just want you to take your time, you know. Take all the time you need, because you have a choice to make. And when I had a choice to make, I chose wrong. Goodnight
03x01 - Time Has Come Today Season 3 / Episode 1: - Time Has Come Today

Dr. Derek Shepherd: [to Meredith] I'm in love with you. I've been in love with you for... ever. I know I'm a little late in telling you. I know I'm a little late.
02x27 - Losing My Religion Season 2 / Episode 27: - Losing My Religion

Dr. Meredith Grey: Just leave me alone.
Dr. Derek Shepherd: I just want to make sure you're alright.
Dr. Meredith Grey: No! I'm not alright? Okay? Are you satisfied? I'm not alright. Because you have a wife, and you call me a whore, and our dog died, and now you're looking at me again. Stop looking at me.
Dr. Derek Shepherd: I am not looking at you. I am *not* looking at you.
Dr. Meredith Grey: You are looking at me. And you watch me. And Finn has plans. And I like Finn. He's perfect for me, and I'm really trying here to be happy, and I feel like I can't breathe. I can't breathe with you looking at me like that so just stop!
Dr. Derek Shepherd: You think I want to look at you? That I wouldn't rather be looking at my wife? I'm married. I have responsibilities. She, she doesn't drive me crazy. She doesn't make it impossible for me to feel normal. She doesn't make me sick to my stomach thinking about my veterinarian touching her with his hands. Man, I would give anything to not be looking at you.
02x27 - Losing My Religion Season 2 / Episode 27: - Losing My Religion

Dr. Meredith Grey: Just leave me alone!
Dr. Derek Shepherd: I just wanted to make sure you're alright.
Dr. Meredith Grey: No! I'm not alright! Okay? Are you satisfied? I'm not alright! Because you have a wife, and you call me a whore, and our dog died. And now, you're looking at me. Stop looking at me!
Dr. Derek Shepherd: I'm not looking at you. I am not looking at you!
Dr. Meredith Grey: You are looking at me! And you watch me! And Finn has plans! And I like Finn, he's perfect for me, and I'm really trying here to be happy, and I can't breathe. I can't breathe with you looking at me like that, so just stop!
Dr. Derek Shepherd: You think I want to look at you? That I wouldn't rather be looking at my wife? I'm married. I have responsibilities. She doesn't drive me crazy, she doesn't make it impossible for me to feel normal, she doesn't make me sick to my stomach thinking about my veterinarian touching her with his hands! Man I would give anything, not to be looking at you!
02x25 - 17 Seconds Season 2 / Episode 25: - 17 Seconds

Dr. Derek Shepherd: What do you want Addison?
Dr. Addison Shepherd: I want you to care. I sleep with your best friend and you walk away. He comes here from New York and rubs it in your face, and still you get a good night's sleep. What do I have to do? Oh, I know. Maybe I should sleep with the vet, because that's what it seems to take to send you into a blind rage. But wait, that won't work either because I'm not Meredith Grey!
02x24 - Damage Case Season 2 / Episode 24: - Damage Case

Dr. Meredith Grey: I never should have told you about George.
Dr. Derek Shepherd: No, it's fine. I'm glad I know about him and the vet. You really get around.
Dr. Meredith Grey: What did you just say to me?
Dr. Derek Shepherd: It's unforgiveable.
Dr. Meredith Grey: I don't remember ever asking you to forgive me.
Dr. Derek Shepherd: So was the knitting a phase? Who's next? Alex? 'Cause I here he likes to sleep around. You two have that in common.
Dr. Meredith Grey: You don't get to call me whore. When I met you I thought I had found the person that I was going to spend the rest of my life with. I was done, so all the boys and all the bars and all the obvious daddy issues, who cared? Because I was done. You left me! You chose Addison! I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore.
Dr. Derek Shepherd: This thing with us is finished. It's over
Dr. Meredith Grey: Finally.
Dr. Derek Shepherd: Yeah, it's done.
Dr. Meredith Grey: It is done.
02x19 - What Have I Done To Deserve This? Season 2 / Episode 19: - What Have I Done To Deserve This?

Dr. Derek Shepherd: I've been paging you
Dr. Miranda Bailey: I'm not on call, I'm on maternity leave
Dr. Derek Shepherd: I've been paging my wife as well, but she hasn't been answering, either. You know where she is.
Dr. Miranda Bailey: Just because I know doesn't mean you should. Some things you just don't get to know, not from me, and really you don't want to know.
Dr. Derek Shepherd: You have to tell me where she is, I saved your husband's life.
Dr. Miranda Bailey: She saved my baby.
Dr. Derek Shepherd: So baby trumps husband?
Dr. Miranda Bailey: Mm-hmm
Dr. Derek Shepherd: Baby trumps husband?
02x19 - What Have I Done To Deserve This? Season 2 / Episode 19: - What Have I Done To Deserve This?

Dr. Derek Shepherd: [Addison is trying to get him to talk right after he wakes up] It's just too early for me to interpret girl flip-out into normal conversation
02x18 - Yesterday Season 2 / Episode 18: - Yesterday

Dr. Mark Sloan: The guys pretty much a goner right?
Dr. Meredith Grey: Sensitivity, I like that in a stranger. Are you new here?
Dr. Meredith Grey, Dr. Derek Shepherd, Dr. Mark Sloan: Visiting. Confounded by all the rain and it's only my first day in town.
Dr. Meredith Grey: You get used to it.
Dr. Mark Sloan: Makes me wanna stay in bed all day.
Dr. Meredith Grey: We just met and already you're talking about bed. Not very subtle.
Dr. Mark Sloan: Subtle's never been my strong suit. So, do you ever go out with co-workers?
Dr. Meredith Grey: I, um, make it a rule not to.
Dr. Mark Sloan: Then I am so glad that I don't work here.
Dr. Meredith Grey: Are you hitting on me? In a hospital?
Dr. Mark Sloan: Would that be wrong?
Dr. Meredith Grey: [Introducing herself] Meredith. [Derek slugs him]
Dr. Meredith Grey: What the hell was that?
Dr. Derek Shepherd: It's Mark.
02x18 - Yesterday Season 2 / Episode 18: - Yesterday

Dr. Addison Shepherd: Put the ice on your hand.
Dr. Derek Shepherd: My hand is fine.
Dr. Richard Webber: Put the damn ice on your two million a year hand. Now, would someone tell me what the hell happened?
Dr. Addison Shepherd: That was Mark.
Dr. Richard Webber: Who's Mark?
Dr. Addison Shepherd: He and Derek used to work together back in New York. And they, we, were all close friends. Until Derek found us in bed together.
Dr. Richard Webber: Did you put your weight behind it?
Dr. Derek Shepherd: Yes sir.
Dr. Richard Webber: Well, alright then.
Dr. Derek Shepherd: What the hell is he doing here?
Dr. Addison Shepherd: I have no idea.
02x18 - Yesterday Season 2 / Episode 18: - Yesterday

Dr. Meredith Grey: Why do people cheat?
Dr. Derek Shepherd: That's a good question.
Dr. Meredith Grey: Why do you think she cheated on you? Were you different then? Were you a bad husband?
Dr. Derek Shepherd: I was a... I was just a little absent. Not that that's an excuse for...
Dr. Meredith Grey: Do you think things would have been different if you had kids?
Dr. Derek Shepherd: Do I think she wouldn't have cheated? I don't know.
02x18 - Yesterday Season 2 / Episode 18: - Yesterday

Dr. Mark Sloan: How come you can forgive her and not me?
Dr. Derek Shepherd: I didn't forgive her and with you I have no obligation to try. [Derek walks off]
Dr. Mark Sloan: Your marriage is over Addison. All you have to do is admit it and then you can come back home with me. I'm going to the bar across the street. Meet me there.
02x17 - (As We Know It) (2) Season 2 / Episode 17: - (As We Know It) (2)

Dr. Derek Shepherd: I'm glad you didn't die today.
02x17 - (As We Know It) (2) Season 2 / Episode 17: - (As We Know It) (2)

Dr. Meredith Grey: Hey.
Dr. Derek Shepherd: Hey. You almost died today.
Dr. Meredith Grey: Yeah, I almost died today.

Dr. Meredith Grey: I can't, I can't remember our last kiss. All I could think about was, "I'm going to die today and I can't remember our last kiss," which is pathetic. But the last time we were together and happy, I... want to be able remember that, and I can't Derek. I can't remember.
Dr. Derek Shepherd: I'm glad you didn't die today.

Dr. Derek Shepherd: It was a Thursday morning, you were wearing that ratty little "Dartmouth" T-shirt you look so good in, the one with the hole in the back of the neck. You'd just washed your hair and you smelled like some kind of... flower. I was running late for surgery. You said you were going to see me later, and you leaned to me, you put your hand on my chest and you kissed me. Soft. It was quick. Kind of like a habit. You know, like we'd do it everyday for the rest of our lives. And you went back to reading the newspaper and I went to work. That was the last time we kissed.

Dr. Meredith Grey: Lavender. My hair smelled like lavender... from my conditioner.
Dr. Derek Shepherd: Lavender. Huh.
02x17 - (As We Know It) (2) Season 2 / Episode 17: - (As We Know It) (2)

Dr. Preston Burke: Derek.
Dr. Derek Shepherd: Preston.
02x17 - (As We Know It) (2) Season 2 / Episode 17: - (As We Know It) (2)

Dr. Derek Shepherd: [Doing life saving brain surgery on Bailey's husband] I just don't want me known as the guy who killed Bailey's husband.
Dr. Preston Burke: [as he's heading out the door to operate on a guy with an unexploded grenade in his chest] And I don't want to be known as the guy who killed everybody else.
02x17 - (As We Know It) (2) Season 2 / Episode 17: - (As We Know It) (2)

Dr. Preston Burke: [Burke and Shepherd walk out of the elevator] Derek.
Dr. Derek Shepherd: Preston.
02x17 - (As We Know It) (2) Season 2 / Episode 17: - (As We Know It) (2)

Dr. Derek Shepherd: [Asking for Meredith] Where is she?
Dr. Richard Webber: She's right here.
Dr. Addison Shepherd: Derek, you're okay... oh... it's going to be okay...
Adele Webber: [to Dr. Webber] That is not the she he was asking for.
02x16 - It's the End of the World (1) Season 2 / Episode 16: - It's the End of the World (1)

Dr. Preston Burke: Dr. Shepherd.
Dr. Derek Shepherd: Dr. Burke. You and I, we've known each other for a while now, right?
Dr. Preston Burke: Yes.
Dr. Derek Shepherd: And we've done several successful surgeries together?
Dr. Preston Burke: Yes.
Dr. Derek Shepherd: Your girlfriend is my ex- girlfriend's best friend.
Dr. Preston Burke: Yes.
Dr. Derek Shepherd: Why can't we call each other by our first names?
Dr. Preston Burke: I don't think so.
Dr. Derek Shepherd: Seriously?
Dr. Preston Burke: Seriously. Dr. Shepherd
Dr. Derek Shepherd: Dr. Burke.
02x16 - It's the End of the World (1) Season 2 / Episode 16: - It's the End of the World (1)

Dylan Young: The chief of surgery has authorized me to tell you you can not stay here
Dr. Derek Shepherd: The chief of surgery doesn't scare me, Dr. Bailey scares me. I'm not gonna be the one to let her husband die.
02x16 - It's the End of the World (1) Season 2 / Episode 16: - It's the End of the World (1)

Dr. George O'Malley: Bailey's in there!
Dr. Richard Webber: Bailey's back? [looks into exam room] O'Malley!
Dr. George O'Malley: She's in labour. Dr Montgomery-Shephard is examining her cervix.
Dr. Richard Webber: I can see that quite clearly. O'Malley, stop looking!
Dr. George O'Malley: Pretty amazing right? Miracle of life...
Dr. Richard Webber: Our Bailey, becoming a mother. Feels good having Bailey back at the hospital, balance has been restored.
Dr. George O'Malley: That's all I'm saying sir.
Dr. Derek Shepherd: Hey guys, what's going on?
Dr. Richard Webber: Bailey's in there.
Dr. Derek Shepherd: Oh Bailey's back? That's excellent! [looks into exam room] And her cervix is being examined by my wife... which is an image I'll never get out of my head. Thanks for the warning.
02x16 - It's the End of the World (1) Season 2 / Episode 16: - It's the End of the World (1)

Dr. Meredith Grey: I have a feeling...
Dr. Derek Shepherd: I get those!
Dr. Meredith Grey: Yeah?
Dr. Derek Shepherd: Yeah!
Dr. Meredith Grey: And?
Dr. Derek Shepherd: If you wait long enough, it'll pass.
Dr. Meredith Grey: Promise?
Dr. Derek Shepherd: I promise. [Meredith walks away and Derek stands there deep in thought]
Dr. Addison Shepherd: Hey! What are you doing?
Dr. Derek Shepherd: Waiting for it to pass...
02x13 - Begin the Begin Season 2 / Episode 13: - Begin the Begin

Dr. Derek Shepherd: There is a land called Passive Agressiva, and *you* are their Queen
02x12 - Grandma Got Run Over By a Reindeer Season 2 / Episode 12: - Grandma Got Run Over By a Reindeer

Dr. Meredith Grey: Tim Epstein, 38, fell off the roof of his house.

Tim Epstein: I was, uh, stringing Hanumas lights and a shingle came loose.
Dr. Isobel 'Izzie' Stevens: Hanumas?
Tim Epstein: Hanumas. Christmukkah. We go all out.
Dr. Isobel 'Izzie' Stevens: [Smiling] Awesome.
Mrs. Epstein: He fell twelve feet.
Tim Epstein: The good news is, my head broke my fall.

Dr. Meredith Grey: Uh, there are no visible deformities, but he's definitely having some focal left arm weakness.
Mrs. Epstein: He'll probably be fine. He's always been a little hard-headed.

Dr. Derek Shepherd: Does your head hurt when you laugh?
Tim Epstein: Is that a bad thing?
Dr. Derek Shepherd: Do you wanna follow my finger with your eyes, please?
Jake Epstein: [to Bailey] I know karate.
Dr. Miranda Bailey: [Flustered] Hmm? Uh... You know, your husband might need a little, uh, quiet, so, there's a cafeteria right down the...
Tim Epstein: No, no. Whoa. Let 'em stay. Pain or no, I don't wanna miss out on the holidays with my kids.

Dr. Derek Shepherd: Who would like to take Mr., uhm, Epstein down for a CT?

Dr. Derek Shepherd: Stevens it is. [Izzie grins]

Dr. Richard Webber: Anxiety attacks, aneurysms and ulcers.
Dr. Miranda Bailey: Must be December.
Patricia: Chief, Adele just called.
Dr. Richard Webber: Tell her I'm in...
Patricia: She knows your not in surgery. And she said to tell you, quote, "We are going to our niece's school pageant this morning. You have known about it for months. And after what you pulled on Thanksgiving...” and then she, started using a great many words I don't feel comfortable repeating.
Dr. Richard Webber: But I have seven surgeons on vacation...
Patricia: And there was something about "divorce".
Dr. Richard Webber: [to Dr. Bailey] You'll have to cover my ulcer excision.
Dr. Miranda Bailey: Yes, sir.

Dr. Richard Webber: The woman is unreasonable. When did watching a six-year-old dressed up like a wise man become... You couldn't hang up the phone?
02x11 - Owner of a Lonely Heart Season 2 / Episode 11: - Owner of a Lonely Heart

Dr. Derek Shepherd: So you're giving up the trailer?
Dr. Meredith Grey: I'm not giving up the trailer, is Addison telling people that I'm giving up the trailer?
Dr. Derek Shepherd: It's just funny, I just would never have pegged you for "that guy"
Dr. Derek Shepherd: What guy?
Dr. Meredith Grey: You know, the "marble bath, private pool, gated community" guy.
Dr. Derek Shepherd: Don't peg me, I'm not peggable.
Dr. Meredith Grey: You're pegged, deal with it. [Later]
Dr. Derek Shepherd: I'm not giving up the trailer.
Dr. Meredith Grey: [smiling] Whatever you say, Dr. Sheperd.

Previous: Dr. Meredith Grey Next: Dr. Cristina Yang

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