The (fictitious) ZIP Code for Port Charles, NY is given as 16543.
The song "Elizabeth", which Lucky Spencer has sung to Elizabeth Webber on various occasions, was actually written by the original Lucky, Jonathan Jackson. ABC made him sell the rights of the song to them, which is why subsequent Luckys have been able to sing the song to Elizabeth.
The show was originally going to be called "Emergency Hospital".
During Steve Hardy and Audrey March's first marriage, the minister was Rachel Ames's father, Bryan Foulger.
At age three, Rachel Ames's daughter Christine Cahill played her son, Tommy.
Luke and Laura Spencer returned to the show on 29 October 1993.
After disappearing from the Port Charles Docks, Laura Spencer returned to the show on November 14, 1983, she was being held captive on the Cassadine Island. (In real life, Genie Francis returned for a six week stint in order to facilitate Anthony Geary's exit from the show.)
Towards 2005 and the beginning of 2006, the virus storyline brought back a herd of immensely popular characters. Rick Springfield had previously returned as Dr. Noah Drake and stayed throughout the beginning. Brad Maule returned as Dr. Tony Jones, and asked the writers to kill off his character. The presumed dead Robert Scorpio returned, bringing in additional viewers and Tristan Rogers has decided to return ornament at the end of March 06, Emma Samms returned as Holly Scorpio, also presumed dead, who held the virus cure for ransom. Bringing back old characters and actors has been such a hit for "General Hospital", they have decided to bring back John Ingle's version of Edward Quartermaine, try to get a storyline for Constance Towers' legendary Helena Cassadine, and plan in the future to bring back Genie Francis (Laura Spencer) to reunite with Anthony Geary's Luke Spencer.
Luke and Laura's wedding in November 1981 remains as the highest watched Daytime event ever with close to 30 million viewers.
The brooch Anna Devane wore on her wedding dress when she wed Duke Lavery actually belonged to Ian Buchanan's grandmother.
While filming on location at Mount Rushmore, Sharon Wyatt's quick ad-libbing saved the show from having to re-shoot after a fan recognized her and walked into the scene saying, "Look, it's Tiffany." In character, she quickly replied, "You must recognize me from one of my movies," and quickly moved the fan from the scene.
John J. York was called upon to do test scenes for the casting of the character, Dominique Taub. He discovered too late that the scene in question involved him being slapped by all of the nine final actresses.
Elizabeth Taylor was the first Helena Cassadine. She loved the show so much that she donated the $2,000 from her stint to charity.
A Martinez looked so much like the original Roy DiLucca, Asher Brauner, that the show was able to use flashbacks as Roy was introduced onto the show.
During Ned and Lois's wedding, head writer Claire Labine made a guest appearance as one of Carmine and Gloria Cerullo's neighbors in New York.
The British Columbia scenes from 1993 to facilitate Luke and Laura's return were filmed in Rochester, New York.
John Ingle's first role was not Edward Quartermaine, but as a Police Commissioner in the mid-1980s.
The show celebrated its 10,000 episode on 17 April 2002.
This is the longest-running dramatic serial on the ABC Network, and is the longest-running daytime drama produced on the West Coast.
During Ned and Lois's trip to Coney Island, Rena Sofer begged the producers for a stand in on the Cyclone. However, Wally Kurth egged her on to try it just once and after thirteen takes, she loved it.
After running over Stuart Damon's feet with her motorized wheelchair during a scene, Anna Lee was jokingly given a crash helmet with the name "The British Bullet".
The role of Robert Scorpio was only supposed to last two days, but ended up staying for twelve years.
After Laura's "death" in 1982, Anthony Geary suggested that Luke Spencer commit suicide. However, Gloria Monty refused to do that to the audience.
Genie Francis asked to come back short term in 2004 in order to "wrap" up the attic storyline, however, she was declined.
Denise Alexander was originally supposed to return in 1993, however, that idea was scrapped and she later returned in 1997 and has been on recurring ever since.
Darlene Conley was in the running for the role of Ruby Anderson. However, Norma Connolly beat her out, and stayed for over 20 years.
There was a point where Emma Samms was torn between her roles on this show and on Dynasty. She was playing a dual role on both shows, dying her hair red for one and back to brown for another. Eventually the Dynasty job won.
A young Demi Moore got her start on General Hospital as Jackie Templeton in 1982.
The Spencer residence is 24 Royal Street.
Judy Lewis played Barbara Vining in the late-'70s, however, as a close friend of Gloria Monty, was asked to be her assistant, and stayed until 1980.