The show's pilot came under fire for depicting mercury additives in childhood vaccines as a credible cause for autism, an idea which had gained a great deal of media attention in the late 1990s but which was thoroughly disproved by the time the episode was produced. The American Academy of Pediatrics asked that a disclaimer to be placed in front of the show, reminding viewers that no mercury is present in routine vaccinations and that the mercury-autism link has been rejected by the medical community. The producers opted to show a disclaimer after the end credits stating that the "persons, companies, products or events" were fictional, referring viewers to the CDC's web site on autism for more information.
Eli jokingly calls Maggie "Veronica Mars". Julie Gonzalo who plays Maggie was a series regular on Veronica Mars.
In "One More Try", Stone asks Maggie if she got her license by watching Legally Blonde over and over. In this episode, Donna's lawyer is played by Alanna Ubach, who plays one of Elle's best friends in the move "Legally Blonde".
While trying to find Stanley Lime in Hawaii, Eli calls Maggie Dekker "Veronica Mars." Maggie Dekker is played by Julie Gonzalo, who also performed as Parker Lee in the television series Veronica Mars.
Eli meets with an attorney to represent for a disbarment hearing. The attorney is played by Alan Rachins who played Douglas Brackman in L.A. Law. The glass behind him shows the name 'McKinley & Brackman - Attorneys at Law', indicating that the character is still practicing law.
The bank that Jordan (Victor Garber) goes into is called Credit Dauphine. Credit Dauphine was the cover for the bank that SD-6 ran their operations out of on the show Alias, which Victor Garber starred in.