- Goof (continuity error): In Walter White's back yard you will notice an outline of a fire place right by their sliding back door, but inside the reverse wall is the dining room/kitchen. Their fire place inside should be on the side of the house.
- Goof (incorrectly regarded as a mistake): In the opening credits, the "Br" and "Ba" in "Breaking Bad" are presented as if they are entries from a periodic table of elements. The additional pieces of information included are atomic number, atomic mass, oxidation states, and electron shell configuration. Each of these is depicted accurately for both Br (bromine) and Ba (barium), except the electron shell configuration for Ba is copied verbatim from Br. Oddly, the periodic table that the entry for Ba is visually extracted from contains the correct information. However, the creators were most likely aware of this, but thought the opening had enough merit to warrant this disregard for correctness under artistic license.
- Goof (factual errors): In the opening credits letters in the names are highlighted in green so as to represent a chemical element symbol. However, Michael Slovis, the Director of Photography, for several of the beginning episodes, they highlight the Ch. There is no chemical element symbol Ch. After a number of episodes they caught it and thereafter they only highlighted the C.
- Goof (miscellaneous): The names (in the opening credits) contain capitalized letter(s) shown in a different color, referring to the chemical symbols of elements of the periodic table of the elements. In the opening credits of the first two seasons, one of them mistakenly implies that Ch is an element. This mistake is corrected in the following seasons.
- Goof (factual errors): A 5000 ml. round bottom boiling flask is neither super expensive or hard to come by. Anyone can order glassware, especially if they have a job like a chemistry teacher.
- Goof (factual errors): Walt accompanies Hank and Gomez on a bust but civilians are not allowed into DEA vehicles by law. (It is possible that Hank knowingly broke the rule.)
- Goof (continuity error): There are several instances where the seasons change from one scene to the next. In particular, Walt walks into his school and there are no leaves on the trees; when he walks out a short time later, the trees are fully green.
- Goof (factual errors): Jesse uses hydrofluoric acid to get rid of the corpse. This is extremely toxic and can only be used in a controlled environment with extreme safety measures. The gloves and masks he puts on are nowhere near enough, let alone them standing near it once the bathtub gives way. They would have suffered extreme lung and eye damage from just standing there.
- Goof (continuity error): When Walter knocks himself out from coughing, he drops and breaks the plate. The initial shot of the broken plate shows 5 broken pieces. However, in the next scene, the plate is shattered to 8 pieces.
- Goof (revealing mistake): In the scene where Walt blows up the BMW with the KEN WINS license plate, Walt pops the hood and then short circuits the battery. In BMW 318i models (the one in the scene), the batteries are actually located in the trunk of the car, instead of the front as shown in this scene.
- Goof (revealing mistake): The black Fender Stratocaster given to Elliot by a friend at his party is a Fender Stratocaster Mexican version. Eric Clapton only played Fender Stratocaster American. When he picks up the guitar, the headstock is from a Mexican made Stratocaster (subtle differences, i.e., the missing Fender logo up the very top).
- Goof (continuity error): In the scene where Walter is drinking orange juice after having cooked, the right ear stem of Walt's eyeglasses is about an inch above his ear. When the camera cuts away to another view, his right ear stem has moved down an inch to be directly above his ear.
- Goof (factual errors): When Walt was talking about drinking, he says that in the 30's they would have been breaking the law. There where no rules against drinking during prohibition, only the sale and distribution of alcohol.
- Goof (errors made by characters, possibly deliberate errors by the filmmakers): When discussing alcohol with Hank, Walton says that if they had been drinking the liquor in 1930, it would have been illegal, and one year later it would have been legal. Prohibition in the United States did not end until the ratification of the 21st Amendment in December, 1933.
- Goof (errors made by characters, possibly deliberate errors by the filmmakers): When talking about melting the lock to gain entry to the chemical warehouse, Walt says that the Nazi rail gun the "Schwerer Gustav," could not be destroyed by bombs, and in the end was destroyed by one man who parachuted in and melted the gun. In reality the Gustav was probably destroyed to prevent its capture. After the siege of Leningrad it was moved back to Germany and not seen again until Allied soldiers discovered it, destroyed, in eastern Germany.
- Goof (crew or equipment visible): In the second scene where Skyler is rubbing ointment onto her stomach, she goes to wipe her hands and the hand + camera of the cameraman behind her becomes visible for a second in the left side of the mirror.
- Goof (factual errors): In the shootout with Tuco, Hank's Glock Model 22 makes two clicking sounds as he pulls the trigger twice after he empties his first magazine. A Glock does not operate this way.
- Goof (anachronisms): Hank asks Pinkman's mother if Jesse still drove that 1989 Chevy Monte Carlo, but vehicle production of the Monte Carlo had stopped with the 1988 model year.
- Goof (errors made by characters, possibly deliberate errors by the filmmakers): Hank refers to Jesse's car as an "89 Monte Carlo." Chevrolet did not offer the Monte Carlo for the 1989 model year. Additionally, the styling of Jesse's car indicates an earlier model year, possibly a 1981 or 1982.
- Goof (factual errors): When an IV is inserted, the needle is removed and only a plastic catheter remains. Walt would not have a needle left in his hand and would therefore be unable to reestablish IV access without new equipment. Also, the angle he inserted the needle would have pierced completely through the vein and the IV fluids would not flow through the tubing.
- Goof (errors made by characters, possibly deliberate errors by the filmmakers): Hank refers to Tuco's rifle as an M16, when it is clearly an M4 (or variant), which, as a DEA agent, Hank would almost certainly know.
- Goof (audio/visual unsynchronized): When Skinny Pete, Badger, and Combo come over to Jesse's, the knocking sound continues after the person at the door, in silhouette, has stopped knocking.
- Goof (errors made by characters, possibly deliberate errors by the filmmakers): When hooking up the chemical battery White identifies the positive as "cathode" and negative as "anode." This is backwards. The anode would be the positive (red) connection.
- Goof (continuity error): Jesse moves into a house divided in two. He lives in the right one but when he comes into the house you can see that the windows are located at the left side of the house, which is his next door.
- Goof (continuity error): When Skyler is in the break room at work making tea, the electrical outlet on the wall behind her is empty. After Ted comes in and asks who brought the churros, in the next shot of Skyler suddenly the coffee maker and microwave are plugged in. Then, in the next shot, they are unplugged again.
- Goof (continuity error): While Jane is eating a Popsicle in Jesse's kitchen, the Popsicle goes from being nearly half-eaten to whole and back again during the course of the conversation.
- Goof (revealing mistake): When Jessie flees his apartment after the argument with his girlfriend, he looks back on the house from the driver's seat. The camera looks through the window of a car that cannot be Jessie's, as it has a much curvier roof line.
- Goof (continuity error): When Jesse is cooking up some eggs for (presumably) breakfast, the first egg he cracks in the pan shows that the first egg yoke (when the shot is from underneath the pan) starts to run, whilst in the next shot, the one from above the pan, where Jesse adds another egg to the pan, you can see both the eggs yolks are still intact.
- Goof (revealing mistake): When Jesse throws the glass cup at the wall (and missing Walter), the periodic table starts to roll up before it gets hit.
- Goof (continuity error): After Jesse smashes the glass against the wall, there is no glass visible anywhere on the floor around Walt.

