- Jason Bateman who plays the doctor in this movie previously played Jeffrey Tambor's son (Arrested Development) and Jennifer Garner's husband (Juno) and yet in this movie he never appears on screen with them.
- Movie Goof (factual errors): Although there is no religion in any form and therefore were no gods, Mark states that the aliens in his screenplay were from Mars, which would obviously have a different name because Mars (the Roman god of war) would have never been made up.
- Movie Goof (incorrectly regarded as a mistake): John Hodgman, as the "Wedding Overseer" looks to be wearing a crucifix. However, upon close examination, it is actually a likeness of Mark holding the "two pizza boxes", matching the image behind the "Wedding Overseer".
- The chapel where Jennifer Garner is getting married near the end of the film is the same chapel she was getting married in in her previous film, Ghosts of Girlfriends Past.
View All: Trivia - Goofs - Quotes
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