I Love You, Man

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• The drum set in Sydney's "Man Cave" is a replica of Keith Moon's (The Who) infamous Vistalite 'Goldfish' set, as seen on the US TV show "The Midnight Special" (1972) in 1975. Moon's set featured a second, unused bass drum filled with water and live goldfish.
• Jason Segel and Paul Rudd reprise their roles in a video shown on Rush (II)'s Time Machine tour. The duo manage to get backstage and meet the band after the performance.
• Movie Goof (revealing mistake): At the office when Peter answers the phone, the screen on the iPhone never turns off as is would in reality.
• The bass that Peter plays "Tom Sawyer" on during his first jam with Sydney is a Fender Geddy Lee Jazz Bass, from Fender's Artist Series of electric basses, and is a near-perfect replica of the instrument that Geddy Lee usually plays onstage with Rush (II). Geddy can be seen playing the original instrument during the Rush show later in the movie.